First studies on COVID-19 showed that ocular manifestations can occur during an acute infection with signs of keratoconjunctivitis in 15.631.6% and positive conjunctival swabs tests in only 3.35.2% [14, 15]. 2020. Invest Ophthalmol Vis Sci. Thus, two possible routes of infection emerge by which SARS-CoV 2 can enter the body via the eyes. These symptoms can be the result of problems like retinal tears and retinal detachments; eye strokes, which occur when a blood clot blocks an artery in the retina; or eye infections - all of. Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, et al. In humans, beside of keratoconjunctivitis, retinal involvement like Cotton wool spots [28] (CWS), microhaemorrhages [29], vascular occlusions [30] or hyperreflective foci [31] has been reported in COVID-19 patients. Virol. Pereira, L. A. et al. JAMA 324, 603605. All patients showed normal findings for anterior and posterior segment of both eyes. 1) the hospitalized group show a lower vessel density compared to non hospitalized and control. Therefore, our data is subjected to selection bias and may overestimate the frequency of some abnormalities found. This study evaluated the ocular findings of patients who recovered from COVID-19 with a mean time of 8236.4 days after the onset of the disease's first symptoms. Mendelson M, Nel J, Blumberg L, Madhi SA, Dryden M, Stevens W, et al. Zhong NS, Zheng BJ, Li YM, Null P, Xie ZH, Chan KH, et al. Napoli PE, Nioi M, dAloja E, Fossarello M. The ocular surface and the coronavirus disease 2019: does a dual ocular route exist? Look for These Symptoms in the Months After COVID Recovery A complete ophthalmological exam including functional and imaging end points (including optical coherence tomography (OCT), OCT angiography) was performed. 91, 157160. Qing H, Li Z, Yang Z, Shi M, Huang Z, Song J, et al. Hypoxia, minor perfusion or vein occlusions can lead to Cotton Wool Spots (CWS), which had been also reported by another study 1 month after illness in 6 of 27 (22%) patients, pointing to an expired inflammation in the posterior segment of the eye in some patients [28].
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